In 2008 we preferred in our IVF Laborary to use a prolonged embryonic cultivation of 120 hours (which is five days after the retrieval of eggs), and we achieved 49,4% of clinical pregnancy per embryo transfer. With prolonged cultivation from 798 embryo transfers, there were 153 (19,1%) where at least one embryo was leaving its embryonal sheath (zona pellucida). In these cases, we achieved 58,2% of clinical pregnancies after embryo transfer (89/153). In women with embryonic transfers that did not leave their zona pellucida, we achieved 52,9% KT/ET (128/242).
The results of Centre of Assisted Reproduction of ISCARE IVF are stated in percentages of clinical pregnancies per embryo transfer, together for IVF and ICSI.
|
Year |
ET Number (embryo trnasfers) |
Number of Clinical Gravidities (KT) |
Success Rate % (KT/ET) |
Average Number of Transfered Embryos |
|
2009 |
724 |
326 |
45% |
1,7 |
|
2008 |
798 |
365 |
45,7% |
1,7 |
|
2007 |
956 |
310 |
32,4% |
1,8 |
|
2006 |
1023 |
270 |
26,4% |
1,8 |
|
2005 |
1079 |
416 |
38,6% |
1,8 |
|
2004 |
994 |
356 |
35,8% |
1,9 |
|
2003 |
1172 |
433 |
37% |
2 |
|
2002 |
1194 |
415 |
34,8% |
2,3 |
|
2001 |
1209 |
439 |
36,3% |
2,4 |
|
2000 |
1231 |
448 |
36,4% |
2,5 |
|
1999 |
1459 |
554 |
38% |
2,8 |
|
1998 |
1316 |
537 |
40,8% |
2,9 |
|
1997 |
1232 |
450 |
36,5 |
3,1 |
Explanations of Results:
The bulk of embryo transfers is done in our centre after the prolonged embryonic cultivation between the 4th and the 5th day after the retrieval of oocytes.
We have the best results after the embryo transfers in the stage of a blastocyst. In the first half of 2008 we had 212 embryo transfers of blastocysts after which there were 121 clinical pregnancies (57% KT/ET).
It is wonderful for the centre of assisted reproduction to have a high percentage of KT/ET but if it is at the cost of the fact that high number of embryos is transferred into the uterus and that clinical pregnancies have to do with a high number of multiple pregnancies, this not a success only but a complication, as well.
At ISCARE, we managed to lower an average number of transferred embryos and thus the numbers of multiple pregnancies well lowered, too.